尼斯人娱乐场官网,金沙城中心娱乐网站

ACE色谱柱|菲罗门色谱柱|手性柱|气相柱|SPE|高效液相色谱柱
Solid-Core Mixed-Mode Stationary Phases

尼斯人娱乐场官网,金沙城中心娱乐网站  

SIELC Technologies has developed mixed-mode Columns based on solid-core-porous-shell particles. This separation media combines the efficiency of solid-core technology with the unique selectivity of Ion-Exchange (IE), reverse phase (RP), surface chemistry and ion-exchange HILIC surface.

Combination of solid core particles and IE with RP or HILIC chemistry offers:

  • Fast separation
  • Working pressure within limits of conventional HPLC
  • Unique selectivity profile
  • Retention of compounds difficult to retain by RP chromatography
  • Increase column loading capacity
  • Adjustment of selectivity by mobile phase pH, ion strength, and organic concentration and composition

尼斯人娱乐场官网,金沙城中心娱乐网站  

Columns available in Solid-Core format with 2.7 µm particles:

Column Ion-exchange Separation mode
Cation exchange RP
Anion exchange RP
Cation exchange HILIC

 

One disadvantage of the solid core support in HPLC is lower capacity when you compare it to regular through porous material. However, the mixed-mode materials demonstrated much higher loading capacity compared to regular RP phases (Nicola H. Davies, Melvin R. Euerby and David V. McCalley, Journal of Chromatography A, Volume 1138, Issues 1-2, 5 January 2007,  65-72). Thus, the mixed-mode surface chemistry compensates for loss of loading capacity of partially non-porous particles.

Mixed mode columns demonstrate 2D characteristics with independent adjustment of degree of retention based on ionic and hydrophobic mechanism
Reverse phase mechanism controls by amount of organic modifier in the mobile phase
Ion-exchange mechanism controls by ion strength and pH of the mobile phase
This property allows to resolve complex mixtures with polar, hydrophobic, ionic, and neutral compounds

 

Some separation examples:

 

全国服务热线: | E-mail:
公司地址:广东省广州市天河区天河北路179号尚层国际大厦13层(510620)
Guangzhou FLM Scientific Instrument Co.Ltd
Floor 13, No.179 of North TianHe Road, GuangZhou, 510620, China
CopyRight © 2002-2022 尼斯人娱乐场官网 版权所有
免责声明 | 斗牛游戏 |
  
扫一扫,添加菲罗门公众号
砸金花牛牛游戏平台,澳门萄京888网址2019牛牛棋牌游戏,皇冠428娱乐网址金沙国际 网址js7779,街机千炮捕鱼无限金币金沙国际通用网址,街机千炮捕鱼2赢话费牛牛牌游戏下载安装,mg555娱乐娱城